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This pioneering work together with future research will ensure confidence in the use of in vitro testing to generate human-relevant and mechanistically driven PoDs that, together with estimates of human exposure, can be used in safety assessments of ingredients in consumer goods products without the need for the generation of new animal data

The efficacy and safety of -nicotinamide mononucleotide (NMN) supplementation in healthy middle-aged adults: A randomized, multicenter, double-blind, placebo-controlled, parallel-group, dose-dependent clinical trial

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