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Limitations Reflect Gaps in Ophthalmologic Monitoring The researchers acknowledged several study limitations, including substantial variability in assessment methods, the absence of a specific ICD-10 code for NAION, and the exclusion of participants with advanced diabetic eye disease, and stressed the need for additional research regarding the relationship between semaglutide and NAION The authors concluded, Treatment with semaglutide in adults was not associated with an increased risk of eye disorders or DR in this study, and future studies are unlikely to change these results
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In this study, most oral semaglutide users received the starting dose of 3.0 mg at first dispensation, which aligned with previous studies in which 5289% of incident and prevalent patients combined received this dose at first dispensation [13, 23]
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