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The intensive lifestyle intervention group achieved greater weight loss (6.0% vs 3.5%) and reductions in glycated haemoglobin (HbA 1c ) as well as in all traditional CVD risk factors, except for LDL-cholesterol

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Optimizacin a largo plazo: La mayora de los efectos secundarios gastrointestinales disminuyen despus de 4-8 semanas de tratamiento a medida que el cuerpo se adapta