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Nicotinamide (niacinamide) does not cause flushing and has fewer side effects, with nausea and liver toxicity reported only at very high intakes ~3 g/day)
Intramuscular treatment can be necessary when the cause creates a persistent absorption problem, when specific surgery has removed the normal absorption pathway, or when clinical risk and adherence support that route
TB500 also helps prevent excess scar tissue, a common problem in tissue healing
These approaches require medical procedures and carry higher costs and risks
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