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That is also the exact window when NSAID-related mucosal risk is highest, because the stomach is already under stress
If gastrointestinal symptoms become severe, temporarily returning to the last tolerated dose followed by more gradual re-escalation may be appropriate
Do not change, adjust, or discontinue any medications or prescribed treatments without your physician's guidance and approval
This is, then, oxidized by cytosolic isocitrate dehydrogenase 1 (IDH1) to -ketoglutarate with the production of NADPH required for the detoxification from reactive oxygen species (ROS
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