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The women on hormone therapy at every checkpoint from 3 to 12 months achieved more weight loss

Relative to comparators, the risk for any of the commonly used cardiovascular end points was estimated to be below 1.0, and for both MACE-4 and MACE-3 (myocardial infarction, stroke, and all-cause death), the upper bounds of the confidence interval calculated around the hazard ratio were decidedly 8.5 %

They improve mitochondrial function, reduce reliance on glycolysis, and restore normal metabolic patterns in multiple tissue types