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Microvascular effects of glucagon-like peptide-1 receptor agonists in type 2 diabetes: a meta-analysis of randomized controlled trials

Clinical studies have shown impressive results: Semaglutide Average weight loss: 1215% of body weight Tirzepatide Average weight loss: 1822% of body weight Many patients lose 1025 kg over 1218 months when combined with healthy eating and physical activity

According to a population pharmacokinetic analysis of pooled data from 19 studies, the PK profiles of healthy and patient groups were statistically indistinguishable (Schneck and Urva 2024)

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