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Although many peptides are relatively stable during handling, avoiding direct high-pressure impact on delicate lyophilized material is considered good laboratory practice and helps preserve the integrity of the freeze-dried cake during dissolution
Substitution in positions 6 and 10 leads to highly active peptides
P.AllenR
Tauro JR, Gemeinhart RA: Extracellular protease activation of chemotherapeutics from hydrogel matrices: A new paradigm for local chemotherapy
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