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In both cohorts, only 37 individuals originally assigned to the placebo completed it without receiving an active treatment (e.g., orforglipron rescue or other obesity medication), which complicates the interpretation of placebo comparisons after week 24

In non-adipose tissues with high rates of triglyceride hydrolysis, such as skeletal muscle and liver, regulation of ATGL activity occurs via a mechanism distinct from that in adipose tissue

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Product Specifications Compound: Semaglutide Purity: 99% (HPLC verified) Form: Lyophilized powder Testing: Third-party Certificate of Analysis available Storage: -20C lyophilized