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To achieve gradually increased expression of LET7, A
Older adults, in particular, may require higher amounts due to absorption challenges or medications that interfere with vitamin absorption
In a primary prevention study among 3,629 cognitively healthy older adults, the Prevention of Alzheimers Disease by Vitamin E and Selenium (PREADViSE) trial, vitamin E supplementation (400 IU/day of supplemental all - rac --tocopheryl acetate [180 mg/day of RRR --tocopherol]) for a mean of 5.4 years had no benefit on prevention of dementia (113)
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