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The knowledge gained from in vitro , preclinical, and animal studies has encouraged a variety of clinical trials investigating the role of dietary choline supplementation in disease progression ( Table 1 ), as well as the association between circulating choline-containing metabolites and disease prognosis or clinical symptoms ( Table 2 )

GLP-1 Receptor Agonists Reduce Colorectal Cancer Risk in IBD Populations Cancer Network Staff Tim Cortese , Russ Conroy Retrospective data showed that GLP-1 receptor agonist use was associated with a 51% reduction in colorectal cancer odds among patients with inflammatory bowel disease