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Data extraction, synthesis and statistical analysis Study screening and selection was carried out by two authors independently with high inter-rater reliability (kappa = 0.93)
Staying hydrated and maintaining electrolyte intake, particularly sodium, potassium and magnesium, also makes a significant difference since dehydration compounds fatigue quickly when thirst signals are blunted by the medication
This matters because muscle supports strength, balance, glucose handling, metabolism, mobility, and long-term weight maintenance
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