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Neuroprotection Against Parkinsons Models MPTP selectively destroys nigrostriatal dopaminergic neurons, producing tremor, rigidity, akinesia, and catalepsy in rodents
[7] Phase 2 Evidence: Weight Loss and Glycemic Control Obesity trial (n=338): dose-dependent loss 24.2% at 12 mg (48 weeks) vs 2.1% placebo
Safety concerns : Mechanistic reasons suggest possible cancer promotion (not initiationbut potentially helping existing cancer cells along)
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