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Targets of Glutathione Melanocytes Methylmercury (mercury) DNA Immune System Specific enzymes Apoptosis (cell death) Vitamins C and E Liver and gallbladder Hyperpigmentation Dull spots Wrinkles (mild) Fine lines (mild) Benefits Skin brightening Evening out discoloration Skin rejuvenation Heart disease prevention Cancer progression prevention Cell damage reduction in liver Improved insulin sensitivity Clinical Studies In a clinical trial testing the efficacy of Glutathione on anti-aging and anti-melanogenic effects, results have shown positive results

Taken together, these observations support a model in which AP2 likely cooperates with the TRIM37TRIM28 complex at a subset of loci, while additional yet-to-be-identified factors may also contribute to targeting or stabilizing the complex at other sites

However, it lacks the clinical trial data and regulatory approval of GLP-1 agonists, and its effects may be more modest